Description: The Emergency Centre for Transboundary Animal Diseases, FAO Viet Nam, has provided various training programmes to animal health workers, in collaboration with the Department of Animal Health. Our experience has shown that animal health workers are a part of the solutions for responsible antimicrobial use and mitigation of antimicrobial resistance. This handbook, therefore, aims to provide first-hand knowledge on antimicrobial resistance and antimicrobial use, serving as a practical guideline for animal health workers to gain a better understanding and advocate them to promote responsible antimicrobial use among animal producers and animal drug sellers and ultimately reduce antimicrobial resistance. (FAO)